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Search Results for " ATP Synthase "

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リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T10404	ATP synthase inhibitor 1		ATPase
	ATP synthase inhibitor 1 is an inhibitor of the c subunit of the F1/FO-ATP synthase complex. It inhibits mitochondrial permeability transition pore (mPTP) opening and does not affect ATP levels.		ATPase
T15373	Gboxin		ATPase , Mitochondrial Metabolism
	Gboxin is an inhibitor of oxidative phosphorylation that targets glioblastoma,inhibits the activity of F0F1 ATP synthase, with antitumour activity.		ATPase , Mitochondrial Metabolism
T1940	BTB06584		RAAS , ATPase
	BTB06584 is an IF1-dependent, selective inhibitor of the mitochondrial F1 Fo-ATPase. BTB06584 is a novel acetohydroxyacid synthase(AHAS) inhibitor, a promising drug target against Mycobacterium tuberculosis (MTB).		RAAS , ATPase
T61649	ATP synthase inhibitor 2
	ATP Synthase Inhibitor 2, a compound targeting Pseudomonas aeruginosa (PA) ATP synthase with an IC50 of 10 μg/mL, fully inhibits the ATP synthesis activity of PA at a concentration of 128 μg/mL [1].
T60877	Mtb ATP synthase-IN-1
	Mtb ATP synthase-IN-1 (compound 6ab) can be used in anti-mycobacterium research. Mtb ATP synthase-IN-1 shoys low cytotoxicity (Vero IC 50 > 64 μg/mL) and acceptable oral bioavailability that has good metabolic stability....
T79004	ATP synthase inhibitor 2 TFA
	ATP Synthase Inhibitor 2 (Compound 22) TFA is a potent inhibitor of Pseudomonas aeruginosa ATP synthase with an IC50 value of 10 μg/mL. It effectively halts ATP synthesis in Pseudomonas aeruginosa at a concentration of 1...
T24111	GSK3i XIII	GSK3 inhibitor XIII,GSK3iXIII,GSK3i-XIII	GSK-3
	GSK3i XIII (GSK3 inhibitor XIII) is a GSK-3 ATP-binding site inhibitor.		GSK-3
T6820	D-α-Hydroxyglutaric acid disodium	D-alpha-Hydroxyglutaric acid disodium salt,Disodium (R)-2-Hydroxyglutarate	ATPase , Others , Reactive Oxygen Species , Endogenous Metabolite , mTOR
	D-α-Hydroxyglutaric acid disodium (Disodium (R)-2-Hydroxyglutarate) is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM.
T21023	Bedaquiline fumarate	TMC 207,R403323,TMC-207,TMC207,R-403323,R 403323	Antibacterial , Antibiotic
	Bedaquiline fumarate (TMC207), a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections. It blocks the proton pump for ATP synthase of mycobacteria. ...		Antibacterial , Antibiotic
T3067	Tideglusib	NP-12,NP031112	GSK-3
	Tideglusib (NP031112), a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3), is with anti-inflammatory and neuroprotective activities.		GSK-3
T36624L	α-Hydroxyglutaric Acid Lithium	α-Hydroxyglutaric Acid Lithium(2889-31-8 Free base)	Decarboxylase , Endogenous Metabolite , mTOR
	α-Hydroxyglutaric Acid Lithium, converted from glutamate in microorganisms and animals, is an inhibitor of α-ketoglutarate-dependent dioxygenase and 5-methylcytosine hydroxylase, and has an inhibitory effect on ATP synth...		Decarboxylase , Endogenous Metabolite , mTOR
T14066	9-ING-41		Apoptosis , GSK-3 , Autophagy
	9-ING-41 is a glycogen synthase kinase-3 inhibitor.		Apoptosis , GSK-3 , Autophagy
T26843	BMS-199264 hydrochloride
	BMS-199264 hydrochloride potently inhibits the ATP hydrolase activity of mitochondrial F1F0 ATP synthase.
T38231	Isoapoptolidin
	Isoapoptolidin is a stable derivative of apoptolidin that demonstrates 10-fold reduced F1FO-ATP synthase inhibitory activity compared to apoptolidin (IC50s = 17 and 0.7 μM, respectively).
T74033	6-Me-ATP
	6-Me-ATP (N6-Methyl-ATP), a N6-modified adenosine triphosphate (ATP) derivative, exhibits strong binding affinity for glycogen synthase kinase 3 (GSK3) and acts as the phosphate group donor in GSK3β-catalyzed phosphoryla...
T35560	SAR502250
	SAR502250 is a potent, selective, ATP-competitive, orally active, and brain-penetrant GSK3 inhibitor with a human GSK-3β IC50 value of 12 nM. It exhibits antidepressant-like activity and is being researched for potential...

Compounds

ATP synthase inhibitor 1

Target: ATPase, Mitochondrial Metabolism

BTB06584

T1940

Synonym:

Target: RAAS, ATPase

ATP synthase inhibitor 2

T61649

Synonym:

Target:

Mtb ATP synthase-IN-1

T60877

Synonym:

Target:

ATP synthase inhibitor 2 TFA

Synonym: GSK3 inhibitor XIII,GSK3iXIII,GSK3i-XIII

Target: GSK-3

D-α-Hydroxyglutaric acid disodium

T6820

Synonym: D-alpha-Hydroxyglutaric acid disodium salt,Disodium (R)-2-Hydroxyglutarate

Target: ATPase, Others, Reactive Oxygen Species, Endogenous Metabolite, mTOR

Bedaquiline fumarate

T21023

Synonym: TMC 207,R403323,TMC-207,TMC207,R-403323,R 403323

Target: Antibacterial, Antibiotic

Tideglusib

T3067

Synonym: NP-12,NP031112

Target: GSK-3

α-Hydroxyglutaric Acid Lithium

T36624L

Synonym: α-Hydroxyglutaric Acid Lithium(2889-31-8 Free base)

Target: Decarboxylase, Endogenous Metabolite, mTOR

9-ING-41

T14066

Synonym:

Target: Apoptosis, GSK-3, Autophagy

BMS-199264 hydrochloride

カタログ番号	製品名	別名	ターゲット
T6323	Oligomycin A	MCH 32	ATPase , Antibiotic , Antifungal
	Oligomycin A (MCH 32) is an inhibitor of ATP synthase, inhibits oxidative phosphorylation and all the ATP-dependent processes occurring on the coupling membrane of mitochondria.		ATPase , Antibiotic , Antifungal
T4861	Trans-Aconitic acid		ATPase , Endogenous Metabolite
	Trans-Aconitic acid is normally present in normal human urine, and it has been suggested that is present in larger amounts with Reye's syndrome and organic aciduria. trans-Aconitic acid is a substrate of enzyme trans-aco...		ATPase , Endogenous Metabolite
T12298	Oligomycin B		Others
	Oligomycin B is an antibiotic isolated from marine Streptomyces, is an eukaryotic ATP synthase inhibitor, induces apoptosis.		Others

天然物製品

Oligomycin A

T6323

Synonym: MCH 32

Target: ATPase, Antibiotic, Antifungal

trans-Aconitic acid

T4861

Synonym:

Target: ATPase, Endogenous Metabolite

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-02530	ATP5B Protein, Mouse, Recombinant (His & Myc & SUMO)	Mouse	E. coli
	Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respirator...
TMPH-00964	ATP5PB Protein, Human, Recombinant (His & Myc)	Human	E. coli
	ATP5PB Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPH-03249	ATP5F1B Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	ATP5F1B Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 59.2 kDa and the accession number is P10719.
TMPH-00967	ATP5F1B Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	ATP5F1B Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli.
TMPH-00966	ATP5F1B Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	ATP5F1B Protein, Human, Recombinant (His) is expressed in Yeast.
TMPH-00226	ATPase subunit g Protein, Bovine, Recombinant (His & Myc)	Bovine	E. coli
	ATPase subunit g Protein, Bovine, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.7 kDa and the accession number is Q28852.
TMPH-00965	ATP5F1A Protein, Human, Recombinant (His)	Human	E. coli
	ATP5F1A Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-00969	ATP5O Protein, Human, Recombinant (GST)	Human	E. coli
	ATP5O Protein, Human, Recombinant (GST) is expressed in E. coli.
TMPY-03609	ATP5D Protein, Human, Recombinant (His)	Human	E. coli
	ATP5D is a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synth...
TMPH-00968	ATP5C1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	ATP5C1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 37.6 kDa and the accession number is P36542.
TMPH-01862	PFAS Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonu...
TMPJ-00732	ASS1 Protein, Human, Recombinant (His)	Human	E. coli
	Argininosuccinate Synthase (ASS1) is an urea cycle enzyme with a tetrameric structure composed of identical subunits. ASS1 is involved in the synthesis of arginine and catalyzes that condensation of citrulline and aspart...
TMPJ-00988	SEPHS1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Selenophosphate synthetase 1 (SEPHS1) belongs to the selenophosphate synthase 1 family, Class II subfamily. It has four different isoforms by alternative splicing. Isoform 1 and isoform 2 are gradually expressed during t...
TMPJ-00979	GSH-S Protein, Human, Recombinant (His)	Human	E. coli
	Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glyci...
TMPY-04137	ATP6V1F Protein, Human, Recombinant (GST)	Human	E. coli
	ATP6V1F encodes a component of vacuolar ATPase mediating acidification. The cDNA and the genomic sequences of ATP6V1F were cloned successfully for the first time from the Giant Panda (Ailuropoda melanoleuca) using revers...
TMPH-02617	COX5A Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase...